Synthesis of Ibuprofen Eugenol Ester and Its Microemulsion Formulation for Parenteral Delivery
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چکیده
منابع مشابه
Sensitive liquid chromatographic assay for the simultaneous determination of ibuprofen and its prodrug, ibuprofen eugenol ester, in rat plasma.
A rapid, sensitive, and specific reverse-phase high-performance liquid chromatography (HPLC) method was developed to quantitate ibuprofen (IBU) and its prodrug, ibuprofen eugenol ester (IEE), simultaneously in rat plasma. IBU, IEE, and the internal standard glycryrrhetic acid (GA) were detected by UV absorption at 230 nm. Extraction recoveries for all compounds ranged between 82.6% and 96.2%. R...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2005
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.53.1246